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Thiamine metabolism

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
thiamine + Pyridine <=> Heteropyrithiamine + 4-methyl-5-(2-hydroxyethyl)-thiazole 2.5.1.2 thiamine pyridinylase
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1-deoxy-D-xylulose_5-phosphate + 2-iminoacetate + Thiocarboxy-[sulfur-carrier_protein] <=> 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl_phosphate + Sulfur-carrier_protein + 2 H2O 2.8.1.10 thiazole synthase
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S-adenosyl-L-methionine + 5-amino-1-(5-phospho-D-ribosyl)imidazole <=> 2-methyl-4-amino-5-hydroxymethylpyrimidine_phosphate + 5''-deoxyadenosine + L-methionine + formate + CO + H+ 4.1.99.17 phosphomethylpyrimidine synthase
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2-(4-methyl-1,3-thiazol-5-yl)ethyl_phosphate + 2-methyl-4-amino-5-hydroxymethylpyrimidine_diphosphate + H+ <=> thiamine_phosphate + diphosphate 2.5.1.3 thiamine phosphate synthase
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2-(2-carboxy-4-methylthiazol-5-yl)ethyl_phosphate + 2-methyl-4-amino-5-hydroxymethylpyrimidine_diphosphate + H+ <=> thiamine_phosphate + CO2 + diphosphate 2.5.1.3 thiamine phosphate synthase
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pyridoxal_5'-phosphate + L-histidine <=> 2-methyl-4-amino-5-hydroxymethylpyrimidine_phosphate not assigned
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Thiamine_aldehyde + O2 + H2O <=> H2O2 + thiamine_acetate 1.1.3.23 thiamine oxidase
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thiamine_diphosphate + phosphate + H+ <=> thiamine_triphosphate + H2O + H+ 3.6.1.28 thiamine-triphosphatase
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N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine + H2O <=> 4-amino-5-aminomethyl-2-methylpyrimidine + formate 3.5.1
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thiamine_diphosphate + ADP <=> thiamine_triphosphate + AMP 2.7.4.3 adenylate kinase
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Sulfur-carrier_protein + ATP <=> Adenylyl-[sulfur-carrier_protein] + diphosphate 2.7.7.73 sulfur carrier protein ThiS adenylyltransferase
2.7.7.80 molybdopterin-synthase adenylyltransferase
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glycine + protein + NAD+ <=> ADP-5-ethyl-4-methylthiazole-2-carboxylate + nicotinamide + [Protein]-dehydroalanine + H2O + H+ 2.4.2.60 cysteine-dependent adenosine diphosphate thiazole synthase
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ADP-5-ethyl-4-methylthiazole-2-carboxylate + H2O <=> 2-(2-carboxy-4-methylthiazol-5-yl)ethyl_phosphate + AMP not assigned
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H+ + pyruvate + D-glyceraldehyde_3-phosphate <=> 1-deoxy-D-xylulose_5-phosphate + CO2 2.2.1.7 1-deoxy-D-xylulose-5-phosphate synthase
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thiamine + ATP <=> H+ + thiamine_diphosphate + AMP 2.7.6.2 thiamine diphosphokinase
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H2O + thiamine <=> H+ + 4-methyl-5-(2-hydroxyethyl)-thiazole + 4-Amino-5-hydroxymethyl-2-methylpyrimidine 3.5.99.2 aminopyrimidine aminohydrolase
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ATP + 4-Amino-5-hydroxymethyl-2-methylpyrimidine <=> H+ + ADP + 2-methyl-4-amino-5-hydroxymethylpyrimidine_phosphate 2.7.1.35 pyridoxal kinase
2.7.1.49 hydroxymethylpyrimidine kinase
2.7.4.7 phosphooxymethylpyrimidine kinase
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glycine + O2 <=> 2-iminoacetate + H2O2 + H+ 1.4.3.19 glycine oxidase
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thiamine_diphosphate + H2O <=> H+ + thiamine_phosphate + phosphate 3.1.3.1 alkaline phosphatase
3.1.3.100 thiamine phosphate phosphatase
3.1.3.2 acid phosphatase
3.6.1
3.6.1.15 nucleoside-triphosphate phosphatase
3.6.1.28 thiamine-triphosphatase
3.6.1.5 apyrase
3.6.1.55 8-oxo-dGTP diphosphatase
3.6.1.6 nucleoside diphosphate phosphatase
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2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl_phosphate <=> 2-(2-carboxy-4-methylthiazol-5-yl)ethyl_phosphate 5.3.99.10 thiazole tautomerase
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thiamine <=> N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine not assigned
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thiamine_phosphate + ATP <=> thiamine_diphosphate + ADP 2.7.1.21 thymidine kinase
2.7.4.12 T2-induced deoxynucleotide kinase
2.7.4.13 (deoxy)nucleoside-phosphate kinase
2.7.4.16 thiamine-phosphate kinase
2.7.4.3 adenylate kinase
2.7.4.4 nucleoside-phosphate kinase
2.7.4.8 guanylate kinase
2.7.4.9 dTMP kinase
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L-tyrosine + S-adenosyl-L-methionine + reduced_acceptor <=> 2-iminoacetate + p-Cresol + 5''-deoxyadenosine + L-methionine + acceptor + 2 H+ 4.1.99.19 2-iminoacetate synthase
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ATP + 4-methyl-5-(2-hydroxyethyl)-thiazole <=> H+ + ADP + 2-(4-methyl-1,3-thiazol-5-yl)ethyl_phosphate 2.7.1.50 hydroxyethylthiazole kinase
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thiamine_phosphate + H2O <=> thiamine + phosphate 3.1.3.1 alkaline phosphatase
3.1.3.100 thiamine phosphate phosphatase
3.1.3.2 acid phosphatase
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[enzyme]-S-sulfanylcysteine + Adenylyl-[sulfur-carrier_protein] + reduced_acceptor <=> AMP + Thiocarboxy-[sulfur-carrier_protein] + [enzyme]-cysteine + acceptor 2.8.1.11 molybdopterin synthase sulfurtransferase
2.8.1.4 tRNA uracil 4-sulfurtransferase
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thiamine + ATP <=> H+ + thiamine_phosphate + ADP 2.7.1.89 thiamine kinase
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L-cysteine + [enzyme]-cysteine <=> L-alanine + [enzyme]-S-sulfanylcysteine 2.8.1.7 cysteine desulfurase
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4-amino-5-aminomethyl-2-methylpyrimidine + H2O <=> 4-Amino-5-hydroxymethyl-2-methylpyrimidine + NH3 3.5.99
3.5.99.2 aminopyrimidine aminohydrolase
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2-methyl-4-amino-5-hydroxymethylpyrimidine_phosphate + ATP <=> 2-methyl-4-amino-5-hydroxymethylpyrimidine_diphosphate + ADP 2.7.1.49 hydroxymethylpyrimidine kinase
2.7.4.7 phosphooxymethylpyrimidine kinase
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thiamine_diphosphate + ATP <=> thiamine_triphosphate + ADP 2.7.4.15 thiamine-diphosphate kinase
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NAD+ + glycine + Sulfide <=> nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + H2O + H+ 2.4.2.59 sulfide-dependent adenosine diphosphate thiazole synthase
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thiamine + O2 <=> H2O2 + Thiamine_aldehyde 1.1.3.23 thiamine oxidase
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